周明兵，男，1975年10月出生，教授，浙江省151人才工程第三层次，浙江省中青年学科带头人。

研究方向

竹子生长发育表观遗传学，竹子快速生长机理

学习与工作经历

2000年9月-2003年7月：贵州大学攻读硕士学位

2006年9月-2010年11月：上海交通大学攻读博士学位

2009年9月-2010年3月：德国亥姆霍兹国家研究中心访问学者

2003年7月至今：    永利3044官网教师

教学工作

研究生课程：蛋白质工程，生物信息学

本科生课程： 细胞与分子生物学，细胞生物学，分子生物学

科研项目

1.毛竹LTR反转录转座子响应环境变化的分子机理，国家自然科学基金项目，2019.1.1-2022.12.31，60万元，主持（1/7   ）

2.毛竹MLE（mariner-like element）转座酶催化机理研究，浙江省自然科学基金重点项目，2019.1.1-2022.12.31，主持（1/6），35万元

3.毛竹LTR反转录转座子转座调控机理及对宿主生物多样性的影响，国家自然科学基金项目，2015.1.1-2018.12.31，87万元，主持（1/8   ）

4.毛竹活性 MITE 的分离及与宿主基因表达调控网络互作机制解析，国家自然科学基金项目，2013.1.1-2016.12.31, 80万元，主持（1/8）

5.竹亚科LTR反转录转座子的分布和增殖模式及对宿主基因组进化的影响，浙江省杰出青年项目，2012.1.1-2016.12.31，30万元，主持（1/1）

6.由居间分生组织调控的毛竹快速拔节生长的分子机理研究,国家自然科学基金项目，2016.1.1-2018.12.31，24万元，2/6

7.超活性mariner-like转座子的构建及在基因标签技术应用的探讨，国家自然科学基金项目，2010.1.1-2013.12.31，31万元，主持（1/8）。

论文与专著

1. 论文：

1.Ramakrishnan M, Yrjälä K, Sharma A, Satheesh V, Cho J, Zhou MB*. (2020). Genetics and genomics of moso bamboo (Phyllostachys edulis): current status, future challenges and biotechnological opportunities towards a sustainable bamboo industry. Food and Energy Security, 2020, 9(4):e229.

2.Tao GY, Ramakrishnan M, Vinod KK, Yrjälä K, Satheesh V, Cho J, Fu Y, Zhou MB*. (2020). Multi-omics analysis reveals cellular pathways for rapid growth of moso bamboo. Tree Physiology.  40(11): 1487–1508.

3.Ramakrishnan M, Zhou M*, Pan C, Hänninen H, Yrjälä K, Vinod KK, Tang D. Affinities of Terminal Inverted Repeats to DNA Binding Domain of Transposase Affect the Transposition Activity of Bamboo Ppmar2 Mariner-Like Element. Int J Mol Sci. 2019, 20(15), 3692.

4.Li S, Ramakrishnan M, Vinod K K, Kalendar R, Yrjälä K, & Zhou M*. (2020). Development and deployment of high-throughput retrotransposon-based markers reveal genetic diversity and population structure of Asian bamboo. Forests, 11(1), 31.

5.Ramakrishnan M, Zhou MB*, Pan CF, Hänninen H, Tang DQ, Vinod KK. Nuclear export signal (NES) of transposases affects the transposition activity of mariner-like elements Ppmar1 and Ppmar2 of moso bamboo. Mob DNA. 2019, 10:35. doi: 10.1186/s13100-019-0179-y. eCollection 2019.

6.Zhou M*, Wu J, Ramakrishnan M, Meng X, Vinod K. Prospects for the study of genetic variation among Moso bamboo wild-type and variants through genome resequencing. Trees, 2019, 33(2):371–381

7.Zhou M*, Zhou Q, Hänninen H. The distribution of transposable elements (TEs) in the promoter regions of moso bamboo genes and its influence on downstream genes. Trees, 2018, 2(2):525–537.

8.Zhou M*, Zhu Y, Bai Y, Hänninen K, Meng X. Transcriptionally active LTR retroelement-related sequences and their relationship with small RNA in moso bamboo (Phyllostachys edulis). Molecular Breeding, 2017, 37:132.

9.Zhou M, Chen A, Zhou Q, Tang D, Hänninen K. A moso bamboo (Phyllostachys edulis) miniature inverted-repeat transposable element (MITE): the possible role of a suppressor. Tree Genetics & Genomes (2017) 13: 129.

10.Zhou M, Hu H, Liu Z, Tang D. Two active bamboo mariner-like transposable elements (Ppmar1 and Ppmar2) identified as the transposon-based genetic tools for mutagenesis. 2016, Molecular Breeding, 36:163.

11.Zhou M*, Liang L, Hänninen K. A transposition-active Phyllostachys edulis LTR retrotransposon. Journal of Plant Research, 2018, 131:203–210.

12.Zhou MB, Hu H, Miskey C, Lazarow K, Ivics Z, Kunze R, Yang G, Izsvák Z, Tang DQ. Transposition of the bamboo Mariner-like element Ppmar1 in yeast. Mol Phylogenet Evol, 2017, 109: 367-374

13.Zhou M, Hu B, Zhu Y. Genome-wide characterization and evolution analysis of long terminal repeat retroelements in moso bamboo (Phyllostachys edulis). Tree Genetics & Genomes, 2017, 13: 43. doi:10.1007/s11295-017-1114-3

14.Zhou M*, Xu C, Shen L, Xiang W, Tang D. Evolution of genome sizes in Chinese Bambusoideae (Poaceae) in relation to karyotype. Trees, 2017, 31(1): 41–48

15.Jiang KY, Zhou, MB*, Yang HY, Fang W. Cloning and functional characterization of PjCAO gene involved in chlorophyll b biosynthesis in Pseudosasa japonica cv. Akebonosuji. Trees, 2016, 30: 1303–1314

16.Zhou MB*, Zheng Y, Liu ZG, Xia XW, Ding-Qin Tang DQ, Fu Y, Chen M. Endo-1,4-b-glucanase gene involved into the rapid elongation of Phyllostachys heterocycla var. pubescens, Trees, 2016, 30: 1259–1274

17.Zhou M*, Tao G, Pi P,  Zhu Y,  Bai Y, Meng X. Genome-wide characterization and evolution analysis of miniature inverted-repeat transposable elements (MITEs) in moso bamboo (Phyllostachys heterocycla). Planta, 2016, 244:775–787.

18.Jiang KY, Zhou MB*. Cloning and functional characterization of PjPORB, a member of the POR gene family in Pseudosasa japonica cv. Akebonosuji. Plant Growth Regulation, 2016, 79(1): 95–106

19.Xia XW, Gui RY, Yang HY, Fu Y, Fang W, Zhou MB*. Identification of genes involved in color variation of bamboo culms by suppression subtractive hybridization. Plant Physiology and Biochemistry. 2015, 97: 156-164

20.Zhou MB*, An MM, Xia XW, Yang HY, Cheng MM, Wang KL, Fang W. Sequencing and phylogenetic analysis of the chloroplast genome of Pseudosasa japonica f. Akebonosuji. Biochemical Systematics and Ecology, 2016, 69:41-50

21.Yang HY, Xia XW, Fang W, Fu Y, An MM, Zhou MB*. Identification of genes involved in spontaneous leaf color variation in Pseudosasa japonica. Genet. Mol.Res., 2015, 14 (4): 11827-11840

22.Zhou MB, Zhong H, Hu JL, Tang DQ. Ppmar1 and Ppmar2: the first two complete and intact full-length mariner-like elements isolated in Phyllostachys edulis. Acta Botanica Gallica: Botany Letters, 2015, 162(2):127-137

23.Zhou MB, Zhang Y, Tang DQ. Characterization and Primary Functional Analysis of BvCIGR, a Member of the GRAS Gene Family in Bambusa ventricosa. Bot Rev, 2011, 77(3): 233-242.

24.Zhou MB, Zhong H, Tang DQ. Isolation and characterization of seventy-nine full-length mariner-like transposases in the Bambusoideae subfamily. J Plant Res, 2011, 124: 607–617

25.Zhou MB, Yang P, Gao PJ, Tang DQ. Identification of differentially expressed sequence tags in rapidly elongating phyllostachys pubescens internodes by suppressive subtractive hybridization. Plant Molecular Biology Reporter, 2011, 29: 224–231

26.Zhou MB, Lu JJ, Zhong H, Liu XM, Tang DQ. Distribution and diversity of PIF-like transposable elements in the Bambusoideae subfamily. Plant Sci, 2010, 179: 257–266.

27.Zhou MB, Lu JJ, Zhong H, Tang KX, Tang DQ. Distribution and polymorphism of mariner-like elements in the Bambusoideae subfamily. Plant Syst Evol, 2010, 289: 1–11  

28.Zhou MB, Zhong H, Zhang QH, Tang KX, Tang DQ. Diversity and evolution of Ty1-copia retroelements in representative tribes of Bambusoideae subfamily. Genetica, 2010, 138: 861–868

29.Zhong H, Zhou MB**, Xu CM, Tang DQ. Diversity and evolution of Pong-like elements in Bambusoideae subfamily. Biochem Syst Ecol, 2010, 38: 750–758

30.Chen WW, Qin QP, Zheng YP, Wang C, Wang S, Zhou MB, Zhang C, Cui YY. Overexpression of Doritaenopsis Hybrid EARLY FLOWERING 4-like4 Gene, DhEFL4, Postpones Flowering in Transgenic Arabidopsis. 2016, Plant Molecular Biology Reporter, 34(1):103–117

31.Chen W, Qin Q, Zhang C, Zheng Y, Wang C, Zhou MB, Cui Y. DhEFL2, 3 and 4, the three EARLY FLOWERING4-like genes in a Doritaenopsis hybrid regulate floral transition. Plant Cell Rep. 2015, 34(12): 2027-2041.

32.Sun XS, Qin QP,Zhang J, Zhang C, Zhou MB, Paek KY, Cui YY. Isolation and characterization of the FVE gene of a Doritaenopsis hybrid involved in the regulation of flowering. Plant Growth Regulation, 2012, 68(1): 77-78

33.Sun XS, Qin QP,Zhang J, Zhang C, Zhou MB, Paek KY, Cui YY.Cloning and characterization of a Doritaenopsis hybrid PRP39 gene involved in flowering time. Plant Cell, Tissue and Organ Culture (PCTOC), 2012, 110(3): 347-357

34.Qin QP, Kaas Q, Zhang C, Zhou LP, Luo XY, Zhou MB, Sun XM, Zhang LL, Paek KY, Cui YY. The Cold Awakening of Doritaenopsis ‘Tinny Tender’ Orchid Flowers: The Role of Leaves in Cold-induced Bud Dormancy Release. J Plant Growth Regul, 2012, 31(2): 139-155

35.Luo XY, Zhang C, Sun XM, Qin QP, Zhou MB, Paek KY, Cui YY. Isolation and characterization of a Doritaenopsis hybrid GIGANTEA gene, which possibly involved in inflorescence initiation at low temperatures. Kor. J. Hort. Sci. Technol., 2011, 29 (2): 135-143

36.Dong WJ, Wu MD, Lin Y, Zhou MB, Tang DQ. Evaluation of 15 caespitose bamboo EST-SSR markers for cross-species/genera transferability and ability to identify interspecies hybrids. Plant Breeding, 2011, 130: 596–600

37.Tang DQ, Lu JJ, Fang W, Zhang S, Zhou MB. Development, characterization and utilization of GenBank microsatellite markers in Phyllostachys pubescens and related species. Mol Breed, 2010, 25: 299-311

38.Lin Y, Lu JJ, Wu MD, Zhou MB, Fang W, Ide Y, Tang DQ. Identification, cross-taxon transferability and application of full-length cDNA SSR markers in Phyllostachys pubescens. Springerplus. 2014, 3:486.

39.刘秀丽，汤定钦，周明兵*. 酵母 Ty1 和 Ty3 转座调控机制研究进展. 微生物学杂志, 2020, 40(2):78-86

40.季航, 周明兵*, 蒋政勤, 郑 浩, 徐芷馨. 毛竹 LTＲ 反转录转座子 PHＲE8 的鉴定与转录模式分析. 核农学报 2020，34( 4) : 0705-0713

41.杨雅倩, 傅鹰. 周明兵*. 毛竹细胞分裂素相关基因鉴定及在笋中表达特征分析. 林业科学, 2019, 55(12):61-73

42.蒋政勤, 周明兵*, 郑浩, 季航, 徐芷馨. 毛竹 Phyllostachys edulis retrotransposon 7（PHRE7）转座子的克隆与鉴定. 2019, 永利3044官网学报, 36(5): 917-927

43.叶家其, 张毓婷, 傅鹰, 周明兵*, 汤定钦. 毛竹茎秆伸长过程中赤霉素生物合成、降解和信号转导关键基因的鉴定及表达分析. 生物工程学报, 2019, 35(6): 1−20

44.潘飞翔, 汤定钦, 周明兵*. 一个毛竹LTR反转录转座子结构鉴定及表达模式分析. 生物工程学报, 2019, 35(3): 445-457

45.张赞一，周明兵*，汤定钦. 毛竹LTR反转录转座子PHRE6的克隆与转录活性分析. 中国细胞生物学学报，2018，40(9): 1466-1478.

46.胡冰杰，周明兵*. 植物中活性MITEs转座子研究进展[J]. 生物工程学报, 2018, 34(2): 204−215.

47.王凯利, 傅鹰, 周明兵*. 毛竹SQUAMOSA启动子结合蛋白SBP家族基因的鉴定及表达模式分析. 林业科学, 2017, 53(12): 50-61.

48.陶贵耘，傅鹰，周明兵*. 竹类植物快速生长的机理研究进展. 农业生物技术学报, 2018, 26(5): 871-887

49.刘静，汤定钦，傅鹰，周明兵*. 模式植物侧芽和竹子笋芽分化发育的研究进展. 2017, 25 (5): 788-804 

50.陈昂，周明兵*，汤定钦，137Cs-r辐照及５-氮杂胞苷处理毛竹种子对其实生苗甲基化水平的影响. 核农学报, 2017, 31(2): 218-224.

51.梁琳琳，周明兵*. 植物活性长末端重复序列反转录转座子研究进展. 生物工程学报, 2016, 32(4): 409-429

52.潘春芳, 汤定钦, 周明兵*. ITm活性转座子及其结构特征分析.中国细胞生物学学报, 2016, 38(1):110-122

53.安苗苗，刘 静，郦 元，周明兵*. 花叶矢竹转录组中的转座子表达分析. 永利3044官网学报. 2016, 33(6): 935-943

54.胡慧，周明兵*，杨萍，汤定钦. 毛竹微型颠倒重复序列转座子PhTourist1 的克隆与分析. 林业科学，2015，51(5)：127-134

55.许冰清，安苗苗，姜可以，徐丽丽，杨海芸，周明兵*. 花叶矢竹叶绿体psbD 基因的克隆与功能分析. 永利3044官网学报，2015，32(4)：557-565

56.徐丽丽，安苗苗，徐冰清，姜可以，徐冰清，杨海芸，周明兵*. 花叶矢竹psaA基因克隆及功能分析. 竹子研究汇刊, 2015, 34(1): 41-48

57.杨海芸，何安国，姜可以，李朝娜，周明兵*. 137Cs-γ射线辐照矢竹类组培苗生物学效应. 核农学报, 2014, 28(11)：1941-1949

58.周倩倩, 周明兵*. 转座酶的人工改造与修饰. 生物工程学报, 2014, 30(10): 1504−1514

59.林翩翩, 白有煌, 周明兵. 毛竹细胞色素P450的基因组学分析. 植物生理学报，2014, 50 (9): 1387-1400

60.姜可以，周明兵*. 竹子分子生物学研究进展. 热带亚热带植物学报，2014, 22(6)：632-642.

61.夏湘婉，黄云峰，周明兵*. 毛竹生物资源多样性. 竹子研究汇刊, 2014, 33(4): 6-15

62.周敏，汤定钦，周明兵*. 一个毛竹典型LTR转座子的克隆、鉴定及进化分析. 竹子研究汇刊, 2014, 33(3):1-10

63.郑丽娜，周明兵*. 毛竹快速拔节过程节间组织cDNA文库的构建与分析. 福建林业科技, 2012, 39（3）：19-23

64.周明兵，王晓飞，汤定钦. 野生型和变异型小佛肚竹cDNA文库的构建. 竹子汇刊, 2005, 24(3): 5-8.

65.贾芳信，周明兵，陈荣，杨海芸，高培军，徐川梅。4种竹子的核型及其基因组大小。林业科学，2016，52(9)：57-66.

66.沈利芬, 项伟波, 范彩廷, 金鹏, 周明兵, 徐川梅. 杨梅开花生物学特性. 永利3044官网学报, 2015, 32(2): 278-284

67.杨萍, 杨潮锋, 周明兵. 重点实验室开放共享机制的探索与实践. 实验室科学, 2015, 18(2): 141-143

68.林新春, 汤定钦, 郭小勤, 周明兵, 杨萍, 张智俊. 分子生物学合作式教学改革与实践. 课程教育研究, 2013, (1): 101-102

69.葛梦，喻卫武，周明兵，王同标，杨萍.  浙江杨梅品种遗传差异的SRAP分析.  浙江林业科技, 2012, 32(5):37-41

70.王月圆，刘向敏，周明兵，汤定钦. 小佛肚竹生氰糖苷合成关键酶CYP79家族同源基因的克隆和鉴定. 永利3044官网学报. 2012, 29(4):510-515

71.张迟，周庐萍，罗小燕，孙小明，秦巧平，周明兵，崔永一. 低温对朵丽蝶兰成花过程中碳水化合物及糖转运蛋白基因表达的影响. 中国农业科学, 2011, 44(8):1670-1677

72.刘政捷, 林源, 周明兵, 汤定钦. 应用微卫星分子标记估算毛竹的异交率. 林业科学，2014, 50 (8): 76-81

73.钟浩，周明兵，白有煌，汤定钦. 毛竹Stowaway-like MITEs转座子的富集与分析. 林业科学，2010, 4(46): 37-42.

74.梁银燕，周明兵，汤定钦. 毛竹简易基因组文库的快速构建. 世界竹藤通讯，2008, 6(2): 14-1.

2. 专著：

75.Ramakrishnan M, Yrjälä K, Satheesh V, and Zhou MB. (2020). Bamboo transposon research: current status and perspectives. Plant Transposable Elements: Methods and Protocols. Edited by. Jungnam Cho. (Springer publication)

76.Tang DQ, Zhou MB. (2018) The Distribution, Evolution, Structural Characteristics, and Functional Analysis of the Mariner-Like Elements in Bamboo. In: Kumar A., Ogita S., Yau YY. (eds) Biofuels: Greenhouse Gas Mitigation and Global Warming. Springer, New Delhi

77.Tang DQ, Zhou MB. Repetitive DNA sequences in phyllostachys pubescens genome, 2011, Chapter 1. @ Bioinformatics: genome bioinformatics and computational biology, editor, Renu Tuteja, United States, ISBN: 9781621009139 (hardcover)

78.周明兵 主编，林木植物生理生化和分子生物学实验指南，陕西人民教育出版社，2015年6月，ISBN: 9787545035537，教材。

3. 专利：

79.一种具有高催化活性的Ppmarl转座酶D332S 突变体及其应用. 周明兵, 汤定钦.   发明专利, ZL201710042523.6, 2020-09-11

80.一种具有高催化活性的Ppmarl转座酶V376A 突变体及其应用. 周明兵, 汤定钦.   发明专利,  ZL201710042731.6, 2020-09-11

81.一种具有高催化活性的Ppmarl转座酶C296I突变体及其应用, 周明兵, 汤定钦. 发明专利, ZL201710042721.2, 2020-09-11

82.一种具有高催化活性的Ppmarl转座酶S171A 突变体及其应用, 周明兵, 汤定钦. 发明专利, ZL201710042725.0, 2020-08-28

83.一种具有高催化活性的Ppmarl转座酶F302Q 突变体及其应用, 周明兵, 汤定钦. 发明专利, ZL201710042522.1, 2020-08-20

*通讯作者，**共同第一作者。

 联系方式

通讯地址：浙江省杭州市临安区武肃街666号，永利3044官网东湖校区智能实验楼S309室

邮    编：311300

邮    箱：zhoumingbing@zafu.edu.cn